Bone marrow trephine biopsy

Leaders Bone marrow trephine biopsy

Trephine biopsies of the bone marrow should be carried out, when clinically indicated, by trained individuals following a standard operating procedure. A bone marrow aspiration should be performed as part of the same procedure. For patient safety and convenience, biopsies are usually performed on the posterior iliac crest. The biopsy specimen should measure at least 1.6 cm and, if it does not, ...

Bone marrow trephine biopsy in lymphoproliferative disease.

Introduction Examination of bone marrow biopsy specimens is a valuable diagnostic procedure in patients with known or suspected lymphoproliferative disorders. ' A bone marrow biopsy specimen may be diagnostic in patients without lymphadenopathy or when there is no conclusive histological evidence from other sites. In some conditions, such as hairy cell leukaemia,2 it is the primary diagnostic p...

Bone-marrow aspiration and trephine biopsy.

Keywords: Bone marrow aspiration, Bone marrow trephine biopsy, Bone marrow examination

Materials and Methods: BMA and BMB were performed on 50 patients. Criteria of inclusion included the main indications for performing this procedure, the availability of full medical records and patient consent. The patients had a male to female sex ratio of 1.6:1 and a wide age range from 4 years to 74 years. Results: In the present study, the main indications for bone marrow examination were c...

Bone marrow trephine biopsy findings in chronic myeloid leukemia.

Sixty patients with chronic myeloid leukemia (CML) underwent bone marrow trephine biopsy at presentation. All the biopsies were decalcified, paraffin-embedded and stained with H&E, Gomori's reticulin and Masson Trichrome. A detailed study of the histology including the morphology and topographic distribution of megakaryocytes was done. 55 patients presented in chronic phase. Of these there were...